Development and Evaluation of Atenolol tablet by using Tamarind Kernel Powder as a Natural Disintegrant

Pharmacy

Disintegrants play a crucial role in the formulation of tablets, facilitating the breakdown of the tablet in the gastrointestinal tract and ensuring the release of the active pharmaceutical ingredient. Synthetic disintegrants are commonly used, but natural alternatives are gaining attention due to their potential benefits, including improved biocompatibility and reduced environmental impact. Tamarind seed powder was extracted and characterized for its physical and chemical properties. Atenolol tablets were formulated using the tamarind seed powder as a disintegrant, and their physicochemical properties, such as hardness, friability, and disintegration time, were evaluated. The tablets were also subjected to in vitro dissolution studies to assess the release of atenolol

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