Preparation and Evaluation of Diclofenac Sodium Sustained Release Tablets Using Synthetic Polymer

May 2024
Vol-10, Issue-3
Paper ID: 24158
ISSN: 2395-4396
Downloads: 0

Abstract & Details

Research Area
Pharmacy
Keywords
Diclofenac sodium Polymer sustain Release HPMC EC
Abstract
Oral drug administration is a popular and convenient method due to its ease of swallowing, self-medication, and economic benefits. Tablets are the most popular oral formulation due to their ease of manufacturing,stability, and tamper-proof nature. Drug release is the process of a drug leaving a product and being subjected to absorption, distribution, metabolism, and excretion. Controlled release dosage forms, such as sustained release (SR) dosage forms, are increasingly popular in modern therapeutics. SR dosage forms provide better control of plasma drug levels, less dosage frequency, less side effects, increased efficacy, and constant delivery. Diclofenac sodium, a non-steroidal drug with potent anti-inflammatory, analgesic, and antipyretic effects, is used for pain relief in conditions like rheumatoid arthritis, osteoarthritis, and acute gout. The study aims to formulate a matrix tablet of diclofenac sodium using wet granulation techniques with different concentrations of HPMC and EC.
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Author Information

# Name Institute / Affiliation
1 Tejas D. Ankush Indrayani Vidya Mandir’s Krishnarao Bhegade Institute of Pharmaceutical Education And Research, Talegaon Dabhade.
2 Yogesh B. Zambare Indrayani Vidya Mandir’s Krishnarao Bhegade Institute of Pharmaceutical Education And Research, Talegaon Dabhade.
3 Vaibhavi V. Sayam Indrayani Vidya Mandir’s Krishnarao Bhegade Institute of Pharmaceutical Education And Research, Talegaon Dabhade.
4 Dr. Sanjay .R. Arote Indrayani Vidya Mandir’s Krishnarao Bhegade Institute of Pharmaceutical Education And Research, Talegaon Dabhade.

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APA Style
Ankush, Tejas D., Zambare, Yogesh B., Sayam, Vaibhavi V., & Arote, Dr. Sanjay .R. (2024). Preparation and Evaluation of Diclofenac Sodium Sustained Release Tablets Using Synthetic Polymer. International Journal of Advance Research and Innovative Ideas In Education, 10(3), 4383-4393.
MLA Style
Ankush, Tejas D., et al. "Preparation and Evaluation of Diclofenac Sodium Sustained Release Tablets Using Synthetic Polymer." International Journal of Advance Research and Innovative Ideas In Education, vol. 10, no. 3, 2024, pp. 4383-4393.
IEEE Style
Tejas D. Ankush, Yogesh B. Zambare, Vaibhavi V. Sayam, and Dr. Sanjay .R. Arote, "Preparation and Evaluation of Diclofenac Sodium Sustained Release Tablets Using Synthetic Polymer," International Journal of Advance Research and Innovative Ideas In Education, vol. 10, no. 3, pp. 4383-4393, 2024.
Vancouver Style
Ankush Tejas D., Zambare Yogesh B., Sayam Vaibhavi V., Arote Dr. Sanjay .R.. Preparation and Evaluation of Diclofenac Sodium Sustained Release Tablets Using Synthetic Polymer. International Journal of Advance Research and Innovative Ideas In Education. 2024;10(3):4383-4393.
Harvard Style
Ankush, Tejas D., Zambare, Yogesh B., Sayam, Vaibhavi V., & Arote, Dr. Sanjay .R. (2024) 'Preparation and Evaluation of Diclofenac Sodium Sustained Release Tablets Using Synthetic Polymer', International Journal of Advance Research and Innovative Ideas In Education, 10(3), pp. 4383-4393.
Chicago Style
Ankush, Tejas D., et al. "Preparation and Evaluation of Diclofenac Sodium Sustained Release Tablets Using Synthetic Polymer." International Journal of Advance Research and Innovative Ideas In Education 10, no. 3 (2024): 4383-4393.
Turabian Style
Ankush, Tejas D., et al. "Preparation and Evaluation of Diclofenac Sodium Sustained Release Tablets Using Synthetic Polymer." International Journal of Advance Research and Innovative Ideas In Education 10, no. 3 (2024): 4383-4393.

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