DEVELOPMENT AND CHARACTERIZATION OF INVASOMES OF TAZAROTENE FOR POTENT ANTI ACNE EFFECT

PHARMACY

Invasomes are novel and flexible vesicles containing a mixture of soy phosphatidylcholine (PC), terpenes, lyso PC, and ethanol with improved skin penetration in comparison with liposomes. Furthermore, invasomes have the same structural constituents as liposomes but contain terpene in their structure. Acne is considered as one of the most widespread skin diseases. When extreme disfiguration occurs, it results in the development of severe consequences among the young people and may result in depression and suicide. Acne vulgaris is the second uppermost reason of suicide among skin diseases. When a person is suffering from acne is compared with an individual who is not suffering from acne than it is found that the former has higher level of anxiety, more socio inhibition and has more aggressiveness. Tazarotene is a compound similar to vitamin A. It helps the skin to renew itself more quickly and may improve the appearance and texture of skin. The brand of tazarotene cream is used to reduce the appearance of fine wrinkles on the face, mottled light and dark skin patches on the face, and benign facial lentigines (non- cancerous freckles) in adults and adolescents who are at least 17 years old.

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