EVALUATION OF FAGONIA INDICA ANTI-TUMOR ACTIVITY AGAINST EHRLICH'S ASCITES (EAC) CARCINOMA IN SWISS ALBINO MICE

Pharmacy

To evaluate the Effect of Fagonia indica extract (FIE) on tumor growth response, hematological studies and measurement of normal peritoneal cells in Ehrlich's ascites carcinoma (EAC) in Swiss albino mice. The intraperitoneal administration of the extract effectively reduced the development of solid tumor mass induced by EAC cells. Notably, significant anti-tumor activity was observed in mice treated with different doses over a 14-day period. The administration of the extracted substance led to a noticeable decrease in tumor volume and successfully reversed the alterations observed in hematological parameters caused by tumor inoculation. These findings strongly support the anti-tumor potential of the extracted substance against EAC-induced tumors, with the effectiveness varying depending on the dosage employed.

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