FORMULATION AND EVALUATION OF PARACETAMOL SUSTAINED RELEASE TABLETS

June 2023
Vol-9, Issue-3
Paper ID: 20861
ISSN: 2395-4396
Downloads: 0

Abstract & Details

Research Area
PHARMACEUTICAL SCIENCES
Keywords
paracetamol sustained release HPMC K100 Ethylcellulose in-vitro drug release
Abstract
The aim of the present work is to prepare paracetamol matrix sustained release tablets wet granulation method using HPMC K100 and Ethylcellulose (F1, F2, F3 and F4) at different concentrations. To assess the flow properties of the powder blend (polymers mixed with the drug). To evaluate physical properties of the polymer matrix based tablets for weight variation, hardness, friability, thickness, drug content, uniformity, disintegration time, and in-vitro drug release Results showed good flowability and compressibility properties for all formulae. Physical properties of the tablets showed increase in polymer ratio there was decrease in friability but increase in hardness in all formulations. F2 formulation shows 99.67% of drug release for upto 12hrs. The study concluded that use of HPMC polymer producing effective stable sustained release
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Author Information

# Name Institute / Affiliation
1 Dr Rangu Nirmala Surabhi Dayakar Rao College of Pharmacy, Rimmanaguda (V), Gajwel (M), Siddipet (D), Telangana (state) 50231, India
2 s vaishnavi Surabhi Dayakar Rao College of Pharmacy, Rimmanaguda (V), Gajwel (M), Siddipet (D), Telangana (state) 50231, India
3 sadaf fathima Surabhi Dayakar Rao College of Pharmacy, Rimmanaguda (V), Gajwel (M), Siddipet (D), Telangana (state) 50231, India
4 aiman Surabhi Dayakar Rao College of Pharmacy, Rimmanaguda (V), Gajwel (M), Siddipet (D), Telangana (state) 50231, India
5 Praveen Surabhi Dayakar Rao College of Pharmacy, Rimmanaguda (V), Gajwel (M), Siddipet (D), Telangana (state) 50231, India
6 Mahesh Surabhi Dayakar Rao College of Pharmacy, Rimmanaguda (V), Gajwel (M), Siddipet (D), Telangana (state) 50231, India

How to Cite

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APA Style
Nirmala, Dr Rangu, vaishnavi, s, fathima, sadaf, aiman, Praveen, & Mahesh (2023). FORMULATION AND EVALUATION OF PARACETAMOL SUSTAINED RELEASE TABLETS. International Journal of Advance Research and Innovative Ideas In Education, 9(3), 4293-4297.
MLA Style
Nirmala, Dr Rangu, et al. "FORMULATION AND EVALUATION OF PARACETAMOL SUSTAINED RELEASE TABLETS." International Journal of Advance Research and Innovative Ideas In Education, vol. 9, no. 3, 2023, pp. 4293-4297.
IEEE Style
Dr Rangu Nirmala, s vaishnavi, sadaf fathima, aiman, Praveen, and Mahesh, "FORMULATION AND EVALUATION OF PARACETAMOL SUSTAINED RELEASE TABLETS," International Journal of Advance Research and Innovative Ideas In Education, vol. 9, no. 3, pp. 4293-4297, 2023.
Vancouver Style
Nirmala Dr Rangu, vaishnavi s, fathima sadaf, aiman, Praveen, Mahesh. FORMULATION AND EVALUATION OF PARACETAMOL SUSTAINED RELEASE TABLETS. International Journal of Advance Research and Innovative Ideas In Education. 2023;9(3):4293-4297.
Harvard Style
Nirmala, Dr Rangu, vaishnavi, s, fathima, sadaf, aiman, Praveen, & Mahesh (2023) 'FORMULATION AND EVALUATION OF PARACETAMOL SUSTAINED RELEASE TABLETS', International Journal of Advance Research and Innovative Ideas In Education, 9(3), pp. 4293-4297.
Chicago Style
Nirmala, Dr Rangu, et al. "FORMULATION AND EVALUATION OF PARACETAMOL SUSTAINED RELEASE TABLETS." International Journal of Advance Research and Innovative Ideas In Education 9, no. 3 (2023): 4293-4297.
Turabian Style
Nirmala, Dr Rangu, et al. "FORMULATION AND EVALUATION OF PARACETAMOL SUSTAINED RELEASE TABLETS." International Journal of Advance Research and Innovative Ideas In Education 9, no. 3 (2023): 4293-4297.

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