DENDRIMERS AS; A NOVEL DRUG CARRIERS.

B. Pharmacy

A new class of polymeric polymers is called dendrimers. A dendrimer normally has symmetrical structure around the core and frequently adopts a spherical three-dimensional layout, which offers a high level of surface usefulness and adaptability. Due to their distinct three-dimensional structure, dendrimers are innovative synthetic polymeric systems with superior physical and chemical properties. Dendrimers are an excellent choice for drug delivery by a variety of routes due to their structural characteristics, such as their form, size, structure, branching, functionality, and density. Particularly, dendrimers three-dimensional architecture allows for the incorporation of a wide range of biologically active substances to create biologically active conjugates. They offer surfaces for the attachment of pharmaceuticals and have the capacity to encapsulate or bind drugs using a variety of processes, including physical encapsulation, electrostatic contact and covalent conjugation. As a result, scientists and researchers are now paying close attention to it. Both bioactive molecules like DNA, heparin, and other polyanion as well as medication moieties are compatible with them. This review contains, history of dendrimer, types of dendrimer, synthesis, mode of action, properties and applications of dendrimers.

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