ANTI BACTERIAL ACTIVITY OF DIFFERENT LEAF EXTRACTS OF Chenopodium giganteum USING TWO GRAM-POSITIVE AND TWO GRAM-NEGATIVE BACTERIA

Pharmacy

In this present research the Histological examination, physiological evaluation, phytochemical screening of leaf extracts of Chenopodium giganteum has been studied. Ethanol, aqueous, chloroform, and pet ether extracts of Chenopodium giganteum was prepared. Phytochemical screening shows presence of carbohydrates, proteins, amino acids, glycosides like saponin and flavonoids, tannins, phenols, alkaloids, and steroids. The physiological evaluation shows ash value %, acid insoluble ash % and water insoluble ash %, loss of drying was found to be 8.1%, extractive value of pet ether extract was found to be 2.3%, chloroform extract 4.5%, ethanol extract 7.2% and water 10.2%. In this study the antibacterial activities of four different extracts of leaves of Chenopodium giganteum against two gram-positive and gram-negative micro-organisms was carried out. Ethanol, aqueous, chloroform, and pet ether extracts of Chenopodium giganteum leaves was prepared. The antibacterial activity of different extracts was assessed and observed for their antibacterial activity against bacteria namely Escherichia coli. Pseudomonas aeruginosa, Staphylococcus aureus and Lacto bacillus using well plate method and were examined for the size of zone of inhibition and minimum inhibition method and were calculated for maximum and minimum concentration.

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