ROLE OF CERTAIN MEDICINAL PLANTS ON ANTI-DEPRESSENT/ACTIVITY

BIOLOGICAL & MEDICAL SCIENCE

Depression is a chronic, potentially fatal disorder that affects individuals all over the world. The medications used to treat this condition have a variety of negative effects and may interact with other medications or foods. Complementary therapies are necessary owing to the drawbacks of the existing medication, such as side effects, which can help reduce depression symptoms and avoid a return of the condition. Additionally, a number of studies have investigated supplementary therapy modalities to enhance patient outcomes for depression purpose. Use of therapeutically beneficial medicinal herbs and phytochemicals is one viable alternative treatment to using traditional antidepressants. Medical herbs and phytochemicals have been shown in studies to have positive effects on depression and its underlying central nervous system mechanism. A chronic, episodic condition called major depressive disorder (MDD) causes disturbances in mood, interest, and vegetative symptoms. Through its effects on the patients' physical, mental, psychological, social, and spiritual wellness, it has a significant impact on their quality of life. Depression is a state of gloomy mood and the avoidance of activities marked by a loss of interest, and difficulty concentrating. Inhibition of NA and 5-HT, as well as MAO-A activation, are contributing factors to the illness. A loss in interest in pleasure, feelings of unworthiness or excessive guilt, a drop in appetite and libido, sleeplessness, and persistent thoughts of death or suicide are only a few of the symptoms. Natural plant products are the subject of current study because they represent a plentiful supply of promising novel medication leads.

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