REVIEW ARTICLE ON DEPRESSION AND ANTI-DEPRESSANT ACTIVITY OF VARIOUS MEDICINAL PLANTS

Pharmacology

Depression, a rising concern in this current world is one of the most common psychological disorders that people regardless of age, gender, occupation experience. It has an impact on the mental as well as physical stability, personal and social relations. Although a wide variety of the synthetic drugs available in the market are used to treat depression, they however are associated with more side effects than they are efficacious. It has been found that only about 30% of patients reacted to the available medications and the remaining did not achieve complete recovery. Hence, many clinical investigations have been conducted to broaden approaches in order to develop an effective antidepressant without side effects. Plants have been used as medicines to treat various ailments since ancient days. Nowadays people prefer herbal medicinal therapies as alternatives to chemical and synthetic drugs to treat various diseases because they believe that natural products are more safe and cause fewer side effects even when used for a long time. A database search was performed using the following terms: depression, major depressive disorder, alternatives treatments, clinical trials, antidepressants, medicinal plant and extracts. Thus, the aim of this review is to enlist some plants which have antidepressant property.

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