Oral Antidiabetic drugs Induced Recurrent Hypoglycemia- A Case Series

PharmD

Diabetes is a chronic disease and its symptoms range from high blood glucose levels and low blood glucose levels. In this study, we are mainly focused on hypoglycemia and its fluctuating factors which are caused by anti-diabetic drugs. Incidence of hypoglycemia in a population is mild-moderate- 45% and severe- 6% In this we are discussing two cases. Case-1 A 70years old female had chief complaints of shortness of breath for 2 days it is insidious in onset and gradual progression from grade-I to grade III, with dry cough occasionally. The patient was asymptomatic, later, her GRBS levels became high which was treated with insulin, and IV fluids and GRBS was 260mg/dl. And diagnosed with dilated cardiomyopathy with moderate LV dysfunction with fluctuating sugar with hyperglycaemia and hypoglycaemia. Case-2 A 65 years old female was brought to the hospital in an unconscious state with chief complaints of repeated episodes of altered sensorium for 1 day relieved with food/ORS intake within a few minutes. and diagnosed with K/C/O breast carcinoma with recurrent hypoglycaemia secondary to oral anti-diabetic usage. We conclude Hypoglycemia symptoms can be treated by providing patient education and upon continuous monitoring, a physician can minimise the risk in an individual and can provide a better quality of life to a patient.

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