FORMULATION & EVALUATION OF VORICONAZOLE OINTMENT FOR TOPICAL DELIVERY

July 2022
Vol-8, Issue-4
Paper ID: 17693
ISSN: 2395-4396
Downloads: 0

Abstract & Details

Research Area
Pharmacy
Keywords
voriconazole polyethylene glycols antifungal activity
Abstract
The present study was undertaken to develop ointment containing voriconazole selectively inhibits 14-alpha-lanosterol demethylation in fungi, preventing the production of ergosterol, an essential constituent of the fungal cell membrane, and resulting in fungal cell lysis. (NCI04). The ointment containing voriconazole was prepared by a fusion method., The specified concentration of polyethylene glycol (PEG) 4000, PEG400 and PEG 600 The amount of voriconazole remains fixed (5 mg) for all the eight formulations whereas the amounts of PEG400 will be used for first four formulations i.e. F-1,F-2,F-3,F-4,and PEG 600 for F-5,F-6,F7 & F-8 formulations respectively. The prepared ointments were evaluated for Physical Examination, Determination of pH, Measurement of viscosity, Spreadability Extrudability In-vitro Drug release study. We can conclude that all the parameters were within the acceptable limits.
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Author Information

# Name Institute / Affiliation
1 CH.Shanthi Priya Surabhi DayakarRao College of Pharmacy
2 Dr Rangu Nirmala Surabhi DayakarRao College of Pharmacy
3 S. Rohini Reddy Surabhi DayakarRao College of Pharmacy

How to Cite

Use the following formats to cite this article in your research.

APA Style
Priya, CH.Shanthi, Nirmala, Dr Rangu, & Reddy, S. Rohini (2022). FORMULATION & EVALUATION OF VORICONAZOLE OINTMENT FOR TOPICAL DELIVERY. International Journal of Advance Research and Innovative Ideas In Education, 8(4), 301-305.
MLA Style
Priya, CH.Shanthi, et al. "FORMULATION & EVALUATION OF VORICONAZOLE OINTMENT FOR TOPICAL DELIVERY." International Journal of Advance Research and Innovative Ideas In Education, vol. 8, no. 4, 2022, pp. 301-305.
IEEE Style
CH.Shanthi Priya, Dr Rangu Nirmala, and S. Rohini Reddy, "FORMULATION & EVALUATION OF VORICONAZOLE OINTMENT FOR TOPICAL DELIVERY," International Journal of Advance Research and Innovative Ideas In Education, vol. 8, no. 4, pp. 301-305, 2022.
Vancouver Style
Priya CH.Shanthi, Nirmala Dr Rangu, Reddy S. Rohini. FORMULATION & EVALUATION OF VORICONAZOLE OINTMENT FOR TOPICAL DELIVERY. International Journal of Advance Research and Innovative Ideas In Education. 2022;8(4):301-305.
Harvard Style
Priya, CH.Shanthi, Nirmala, Dr Rangu, & Reddy, S. Rohini (2022) 'FORMULATION & EVALUATION OF VORICONAZOLE OINTMENT FOR TOPICAL DELIVERY', International Journal of Advance Research and Innovative Ideas In Education, 8(4), pp. 301-305.
Chicago Style
Priya, CH.Shanthi, Dr Rangu Nirmala, and S. Rohini Reddy. "FORMULATION & EVALUATION OF VORICONAZOLE OINTMENT FOR TOPICAL DELIVERY." International Journal of Advance Research and Innovative Ideas In Education 8, no. 4 (2022): 301-305.
Turabian Style
Priya, CH.Shanthi, Dr Rangu Nirmala, and S. Rohini Reddy. "FORMULATION & EVALUATION OF VORICONAZOLE OINTMENT FOR TOPICAL DELIVERY." International Journal of Advance Research and Innovative Ideas In Education 8, no. 4 (2022): 301-305.

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