FORMULATION DESIGN AND EVALUATION OF ORODISPERSIBLE TABLET OF ACETYLCYSTEINE USING SUPPERDISINTEGRANT.

July 2022
Vol-8, Issue-4
Paper ID: 17683
ISSN: 2395-4396
Downloads: 0

Abstract & Details

Research Area
pharmacy
Keywords
Acetylcysteine Sodium starch stearate glycolate Polymethacrylate Microcrystalline cellulose Lactose and Mannitol
Abstract
The aim of this work is to formulate and evaluate oral dispersing tablets of acetylcysteine to prevent disease associated with respiratory system mainly in bronchioles. Method which used for Preparation of tablet is direct compression method, with various super disintegrants like sodium starch glycolate, croscarmallose sodium, and Crospovidone at various concentrations (2%-20%). A total of eleven formulations were made using one type of super disintegrants for each formulation. Fourier Transmission InfraRed (FT-IR) and Differential Scanning Calorimetry studies (DSC) were performed to ensure the compatibility of drug with the super disintegrants. It was found to be satisfactory. The results of recompression studies reveals that the powder blends of all formulations acquire good flow properties. From the results of post compression studies for tablets of all formulations, it was concluded that the formulation containing 10% crospovidone as super disintegrants remerged as overall best formulation with lowest disintegration time and highest drug release rate.
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Author Information

# Name Institute / Affiliation
1 Shaikh Mujeeb Musa ali allana college of pharmacy
2 Tamboli Saifali ali allana college of pharmacy
3 Afsar Shaikh ali allana college of pharmacy
4 Khan G J ali allana college of pharmacy
5 Amsari Hammad ali allana college of pharmacy
6 Kasim Patel ali allana college of pharmacy
7 Mohd. Shoeb Nawaz ali allana college of pharmacy
8 Patel Raihan ali allana college of pharmacy

How to Cite

Use the following formats to cite this article in your research.

APA Style
Musa, Shaikh Mujeeb, Saifali, Tamboli, Shaikh, Afsar, J, Khan G, Hammad, Amsari, Patel, Kasim, Nawaz, Mohd. Shoeb, & Raihan, Patel (2022). FORMULATION DESIGN AND EVALUATION OF ORODISPERSIBLE TABLET OF ACETYLCYSTEINE USING SUPPERDISINTEGRANT.. International Journal of Advance Research and Innovative Ideas In Education, 8(4), 294-300.
MLA Style
Musa, Shaikh Mujeeb, et al. "FORMULATION DESIGN AND EVALUATION OF ORODISPERSIBLE TABLET OF ACETYLCYSTEINE USING SUPPERDISINTEGRANT.." International Journal of Advance Research and Innovative Ideas In Education, vol. 8, no. 4, 2022, pp. 294-300.
IEEE Style
Shaikh Mujeeb Musa, Tamboli Saifali, Afsar Shaikh, Khan G J, Amsari Hammad, Kasim Patel, Mohd. Shoeb Nawaz, and Patel Raihan, "FORMULATION DESIGN AND EVALUATION OF ORODISPERSIBLE TABLET OF ACETYLCYSTEINE USING SUPPERDISINTEGRANT.," International Journal of Advance Research and Innovative Ideas In Education, vol. 8, no. 4, pp. 294-300, 2022.
Vancouver Style
Musa Shaikh Mujeeb, Saifali Tamboli, Shaikh Afsar, J Khan G, Hammad Amsari, Patel Kasim, et al. FORMULATION DESIGN AND EVALUATION OF ORODISPERSIBLE TABLET OF ACETYLCYSTEINE USING SUPPERDISINTEGRANT.. International Journal of Advance Research and Innovative Ideas In Education. 2022;8(4):294-300.
Harvard Style
Musa, Shaikh Mujeeb, Saifali, Tamboli, Shaikh, Afsar, J, Khan G, Hammad, Amsari, Patel, Kasim, Nawaz, Mohd. Shoeb, & Raihan, Patel (2022) 'FORMULATION DESIGN AND EVALUATION OF ORODISPERSIBLE TABLET OF ACETYLCYSTEINE USING SUPPERDISINTEGRANT.', International Journal of Advance Research and Innovative Ideas In Education, 8(4), pp. 294-300.
Chicago Style
Musa, Shaikh Mujeeb, et al. "FORMULATION DESIGN AND EVALUATION OF ORODISPERSIBLE TABLET OF ACETYLCYSTEINE USING SUPPERDISINTEGRANT.." International Journal of Advance Research and Innovative Ideas In Education 8, no. 4 (2022): 294-300.
Turabian Style
Musa, Shaikh Mujeeb, et al. "FORMULATION DESIGN AND EVALUATION OF ORODISPERSIBLE TABLET OF ACETYLCYSTEINE USING SUPPERDISINTEGRANT.." International Journal of Advance Research and Innovative Ideas In Education 8, no. 4 (2022): 294-300.

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