FORMULATION DEVELOPMENT AND EVALUATION OF NAIL LACQUER OF POSACONAZOLE FOR TREATMENT ONYCHOMYCOSIS

April 2021
Vol-7, Issue-2
Paper ID: 14076
ISSN: 2395-4396
Downloads: 0

Abstract & Details

Research Area
Pharmaceutics
Keywords
Posaconazole antifungal nail lacquer nitrocellulose in-vitro diffusion.
Abstract
The aim of the study was to formulate and develop the nail lacquer of Posaconazole for treatment of onychomycosis. Posaconazole belong to class of triazole antifungal agent. Posaconazole exhibits broad-spectrum antifungal activity against a variety of yeasts and moulds including species of Candida albicans, majority used for the treatment of onychomycosis. Posaconazole act as an inhibitor of the enzyme lanosterol 14α- demethylase, which catalyses an essential step in ergosterol biosynthesis. This particular drug had been utilized in treatment of onychomycosis. Recently the use of nail lacquer has been proposed for this transungual drug delivery. Nail lacquer are used in finger nail and toe nails of human beings. Drugs like amorolfine and ciclopirox have been already marketed as nail lacquer for the treatment of onychomycosis. Posaconazole has low solubility and high permeability in order to treat disease formulation have been approach to modified dosage form as per need. Solvent casting method can be employed for preparation of nail lacquer.
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Author Information

# Name Institute / Affiliation
1 Patel Namrata Ashwinbhai Smt. B.N.B Swaminarayan Pharmacy College Salvav, Vapi
2 MR. Ajay Talele N Smt. B.N.B Swaminarayan Pharmacy College Salvav, Vapi
3 DR. ANURADHA P. PRAJAPATI Smt. B.N.B Swaminarayan Pharmacy College Salvav, Vapi
4 DR. SACHIN B. NARKHEDE Smt. B.N.B Swaminarayan Pharmacy College Salvav, Vapi

How to Cite

Use the following formats to cite this article in your research.

APA Style
Ashwinbhai, Patel Namrata, N, MR. Ajay Talele, PRAJAPATI, DR. ANURADHA P., & NARKHEDE, DR. SACHIN B. (2021). FORMULATION DEVELOPMENT AND EVALUATION OF NAIL LACQUER OF POSACONAZOLE FOR TREATMENT ONYCHOMYCOSIS. International Journal of Advance Research and Innovative Ideas In Education, 7(2), 1457-1468.
MLA Style
Ashwinbhai, Patel Namrata, et al. "FORMULATION DEVELOPMENT AND EVALUATION OF NAIL LACQUER OF POSACONAZOLE FOR TREATMENT ONYCHOMYCOSIS." International Journal of Advance Research and Innovative Ideas In Education, vol. 7, no. 2, 2021, pp. 1457-1468.
IEEE Style
Patel Namrata Ashwinbhai, MR. Ajay Talele N, DR. ANURADHA P. PRAJAPATI, and DR. SACHIN B. NARKHEDE, "FORMULATION DEVELOPMENT AND EVALUATION OF NAIL LACQUER OF POSACONAZOLE FOR TREATMENT ONYCHOMYCOSIS," International Journal of Advance Research and Innovative Ideas In Education, vol. 7, no. 2, pp. 1457-1468, 2021.
Vancouver Style
Ashwinbhai Patel Namrata, N MR. Ajay Talele, PRAJAPATI DR. ANURADHA P., NARKHEDE DR. SACHIN B.. FORMULATION DEVELOPMENT AND EVALUATION OF NAIL LACQUER OF POSACONAZOLE FOR TREATMENT ONYCHOMYCOSIS. International Journal of Advance Research and Innovative Ideas In Education. 2021;7(2):1457-1468.
Harvard Style
Ashwinbhai, Patel Namrata, N, MR. Ajay Talele, PRAJAPATI, DR. ANURADHA P., & NARKHEDE, DR. SACHIN B. (2021) 'FORMULATION DEVELOPMENT AND EVALUATION OF NAIL LACQUER OF POSACONAZOLE FOR TREATMENT ONYCHOMYCOSIS', International Journal of Advance Research and Innovative Ideas In Education, 7(2), pp. 1457-1468.
Chicago Style
Ashwinbhai, Patel Namrata, et al. "FORMULATION DEVELOPMENT AND EVALUATION OF NAIL LACQUER OF POSACONAZOLE FOR TREATMENT ONYCHOMYCOSIS." International Journal of Advance Research and Innovative Ideas In Education 7, no. 2 (2021): 1457-1468.
Turabian Style
Ashwinbhai, Patel Namrata, et al. "FORMULATION DEVELOPMENT AND EVALUATION OF NAIL LACQUER OF POSACONAZOLE FOR TREATMENT ONYCHOMYCOSIS." International Journal of Advance Research and Innovative Ideas In Education 7, no. 2 (2021): 1457-1468.

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