Formulation Development and Evaluation of Fast Dissolving Films of Anti-asthmatic drug

Pharmaceutics

Asthma is a chronic disease that affects the airways of your lungs. Doxofylline Bioavailability is 63% due to hepatic first pass metabolism. Fast dissolving films have become a novel approach to oral drug delivery system because it provides convenience and ease of use over other solid dosage forms. The principle of doxofylline FDFs preparation offers a simple and practical approach to achieve quick onset of action for the dosage form and bypass the hepatic first pass effect of drug leads to reduction of dose which can lead to reduction in side effect associated with the drug. The films were prepared by solvent casting method. The prepared films were evaluated for thickness, disintegration time, folding endurance, drug release, and drug content.

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.