FAST DISSOLVING TABLET- BENEVOLENCE FOR THE SOCIETY

Pharmacy

Fast dissolving tablets (FDT’s) are becoming more trendy in geriatric patients as it provides better patient-compilance, fast-action, and moreover; easy to administer even without water. Even they have played an emerging role in pediatrics patients because of incomplete development of muscular and nervous system. FDT’s are disintegrating or dissolve quickly in the saliva providing rapid onset of action. With the aid of superdisintegrants (excipients), the normal tablets/ capsules pharmacological-action has been enhanced; leading to what we say fast dissolving tablets. FDTs have advantages such as easy portability and manufacturing, accurate dosing, good chemical and physical stability nd an ideal alternative for geriatric and pediatric patients. FDTs have disintegrated quickly, absorb faster so, in vitro drug release time improve and this property of drugs (dosage form) enhanced bioavailability. FDT formulations have the advantage of both conventional tablet formulation and liquid dosage form. There are several technologies that are conventional or patented based on spray drying, cotton candy process, sublimation, melt granulation, direct compression freezes drying/lyophilization, phase transition process, mass extrusion, etc. have been developed for manufacturing of FDTs. In this review contain brief information about FDTs including definition, advantages, needs or requirements of FDTs, salient features of FDTs, limitations, challenges to developing FDT, marketed formulations of fast dissolving tablets, etc.

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.