Formulation And Evaluation of Herbal Oil In The Treatment of Rheumatoid Arthritis

Pharmacy

Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by inflammation, joint pain, and progressive cartilage damage. Conventional treatments often have adverse effects, leading to increased interest in herbal formulations as alternative therapies. This study focuses on the formulation and evaluation of an herbal oil for the treatment of RA, utilizing medicinal plants with anti-inflammatory, analgesic, and antioxidant properties. A polyherbal oil was prepared using extracts from Tridax procumbens , Ashwagandha , Indian Bdellium , sesame oil as a base. These ingredients were selected for their well-documented pharmacological activities in reducing inflammation and alleviating joint pain. The oil was formulated using the infusion technique, followed by physicochemical evaluations, including viscosity, pH, spreadability, and stability studies. The therapeutic efficacy of the herbal oil was assessed using patch test . The results demonstrated significant inhibition of inflammatory markers, reduced paw swelling, and improved mobility in treated subjects compared to the control group. Additionally, no significant adverse effects were observed, confirming the safety profile of the formulation.

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