Formulation And Evalution of Itraconazole Antifungal Nail Lacquar

pharmacy

In present, this study an antifungal nail polish was developed. The goal was to provide sustained release of anti-inflammatory drugs over a longer period of time, reducing the frequency of administration, increasing clinical effectiveness, and improving patient compliance. Fungal nail disease, onychomycosis, the most common nail disorder, requires effective systemic treatment given the adverse effects of antifungal therapy. Onychomycosis is a common nail infection that mostly affects the elderly and athletes. Antibiotics such as itraconazole are one of the drugs of choice in the treatment of onchomycosis. The current study focused on the preparation and development of itraconazole-filled nail polish. The main aim of this study is to develop and evaluate a chitosan nanoparticle-based hydrogel for the treatment of onychomycosis. There are different nail treatments such as cream, solution, gel and nail polish. The nail is a small piece of muscle. Therefore, nail polish will be more effective than other methods, especially oral application. - The nail polish is prepared using a mixture of nitrocellulose, ethyl cellulose, ethyl acetate, salicylic acid (acts as a penetrant), dibutyl phthalate and oils of various extracts and Syzygium Aromaticum of Calendula Officinalis, Origanum vulgare, Allium sativum, Melaleucaalternifolia, cymbopogon, Ocimumtenuflorum and Menthapiperita .

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