Review On A Synthesis of Benzotriazole

pharmacy

Benzotriazoles are a derivative of a nitrogen-containing heterocycle with three nitrogen atoms located at the 1st, 2nd, and 3rd positions. Each nitrogen atom contains lone pairs of electrons in an unshared state, allowing the five-membered ring to exhibit tautomeric forms. This bicyclic heterocyclic system, consisting of three nitrogen atoms and a fused benzene ring, showcases a wide range of biological and pharmacological properties. The synthesis of benzotriazole involves combining benzene-1,2-diamine and carboxylic acid. Benzotriazole and its derivatives play a crucial role in medicinal chemistry, being utilized by chemists to address various therapeutic conditions. This paper discusses the application, principles, and chemistry of benzotriazoles, as well as provides an overview of the synthesized drug method.

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