A REVIEW ON PHARMACOLOGICAL EVALUATION OF MORINGA OLEIFERA LEAF EXTRACT FOR ANALGESIC ACTIVITY BY USING MICE

Pharmacology

Moringa oleifera is highly valued plant available in many countries of the tropic and subtropics. Moringa oleifera leaf are a potential source of phytochemical ingredients claimed to have analgesic property including Anti- inflammatory and Anti-oxidant properties. Pain is an disagreeable, nasty, obnoxious sensation, which in many cases represents the only symptom for the diagnosis of several diseases and Disorders. The present study is undertaken to evaluate the analgesic activity of Moringa oleifera using acetic acid induced writhing test and Eddy’s hot plate test and the Tail flick method. In this study of Analgesic activity detection includes the three tests :1] Acetic Acid Induced Writhing Test , 2] Eddy’s Hot Plate Test , 3] Tail Flick Method. The ethanolic leaf extract of Moringa oleifera exhibited analgesic activity in both models showing its both central and peripheral analgesic actions. Studies are needed to isolate the active constituents responsible for the observed effect and to reveal the possible mechanism of action responsible for its anti- nociceptive activity.

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