Dostarlimab: Pharmacological Analysis & Clinical Applications in Therapy of Cancer

Tejal Girish Pathak; Lokesh Pramod Joshi

Dostarlimab: Pharmacological Analysis & Clinical Applications in Therapy of Cancer

February 2023

Vol-9, Issue-1

Paper ID: 19272

ISSN: 2395-4396

Downloads: 0

Abstract & Details

Research Area

Pharmaceutics, Pharmacy.

Keywords

Anti PD-1 antibody Dostarlimab Clinical trials JEMPERLI

Abstract

Dostarlimab , which is sold under brand name JEMPERLI is a PD-1 monoclonal antibody which is effective for treatment of adult patient with mis-match repair deficient (dMMR), recurrent or advanced endometrialcancer that has improvement on oor upgoing therapy with platinum containing regimen. This indication was granted fast approval based on the rate of tumor respnse and duration of response by test of FDA. The clinical trial performed in June 2022 , NCT04165772 shows 100% remission rate for rectal cancer. This clinical research shows proof that we can match a tumor and the genetics of what is driving it, with therapy. This clinical research currently enrolling patients with gastric, prostate, and pancreatic cancers. Dostarlimab is being adviced for rectal cancer. The present review is an effort to share the knowledge regarding dostarlimab.

License

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Author Information

#	Name	Institute / Affiliation
1	Tejal Girish Pathak	P.G.Collge of Pharmaceutical Science & Research , Nandurbar
2	Lokesh Pramod Joshi	P.G.Collge of Pharmaceutical Science & Research , Nandurbar

How to Cite

Use the following formats to cite this article in your research.

APA Style

Pathak, Tejal Girish & Joshi, Lokesh Pramod (2023). Dostarlimab: Pharmacological Analysis & Clinical Applications in Therapy of Cancer. International Journal of Advance Research and Innovative Ideas In Education, 9(1), 1820-1825.

MLA Style

Pathak, Tejal Girish, and Lokesh Pramod Joshi. "Dostarlimab: Pharmacological Analysis & Clinical Applications in Therapy of Cancer." International Journal of Advance Research and Innovative Ideas In Education, vol. 9, no. 1, 2023, pp. 1820-1825.

IEEE Style

Tejal Girish Pathak and Lokesh Pramod Joshi, "Dostarlimab: Pharmacological Analysis & Clinical Applications in Therapy of Cancer," International Journal of Advance Research and Innovative Ideas In Education, vol. 9, no. 1, pp. 1820-1825, 2023.

Vancouver Style

Pathak Tejal Girish, Joshi Lokesh Pramod. Dostarlimab: Pharmacological Analysis & Clinical Applications in Therapy of Cancer. International Journal of Advance Research and Innovative Ideas In Education. 2023;9(1):1820-1825.

Harvard Style

Pathak, Tejal Girish & Joshi, Lokesh Pramod (2023) 'Dostarlimab: Pharmacological Analysis & Clinical Applications in Therapy of Cancer', International Journal of Advance Research and Innovative Ideas In Education, 9(1), pp. 1820-1825.

Chicago Style

Pathak, Tejal Girish and Lokesh Pramod Joshi. "Dostarlimab: Pharmacological Analysis & Clinical Applications in Therapy of Cancer." International Journal of Advance Research and Innovative Ideas In Education 9, no. 1 (2023): 1820-1825.

Turabian Style

Pathak, Tejal Girish and Lokesh Pramod Joshi. "Dostarlimab: Pharmacological Analysis & Clinical Applications in Therapy of Cancer." International Journal of Advance Research and Innovative Ideas In Education 9, no. 1 (2023): 1820-1825.