FORMULATION & EVALUATION OF ROXITHROMYCIN TABLET FOR RESPIRATORY TRACT INFECTION

Mr. Abhijeet Kastode; Dnyaneshwar S Vyavhare; Dr.Megha Salve

FORMULATION & EVALUATION OF ROXITHROMYCIN TABLET FOR RESPIRATORY TRACT INFECTION

May 2025

Vol-11, Issue-3

Paper ID: 26669

ISSN: 2395-4396

Downloads: 0

Abstract & Details

Research Area

Pharmacy

Keywords

Dual release system Dual drug delivery system Roxithromycin Factorial design HPMC K4M HPMC K15M Floating lag time.

Abstract

The aim of this study was to develop microspheres based orodispersible tablets of roxithromycin using the solvent evaporation technique. The microspheres were formulated in to orodispersible tablets using direct compression technique by central composite design. The objective of the study was to analyze the effect of concentration of eudragit RS100 (F1) and concentration of polyvinyl alcohol (F2), on the entrapment efficiency of the drug. Tablets were evaluated for physical characteristics viz. weight variation, hardness, friability, disintegration time and in-vitro dissolution study. The hardness and weight variation of the tablet were found 5.17 ± 0.76 kg/cm and 644.6 ± 6.3 mg, respectively. Friability of tablets was found 0.74 which is less than 1% or in the acceptable limit. Thikness of tablet were found 6.30 ± 0.10 mm. The drug release data were subjected to drug release kinetics study.

License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author Information

#	Name	Institute / Affiliation
1	Mr. Abhijeet Kastode	Shivajirao Pawar College of Pharmacy
2	Dnyaneshwar S Vyavhare	Shivajirao Pawar College of Pharmacy
3	Dr.Megha Salve	Shivajirao Pawar College of Pharmacy

How to Cite

Use the following formats to cite this article in your research.

APA Style

Kastode, Mr. Abhijeet, Vyavhare, Dnyaneshwar S, & Salve, Dr.Megha (2025). FORMULATION & EVALUATION OF ROXITHROMYCIN TABLET FOR RESPIRATORY TRACT INFECTION. International Journal of Advance Research and Innovative Ideas In Education, 11(3), 1735-1752.

MLA Style

Kastode, Mr. Abhijeet, et al. "FORMULATION & EVALUATION OF ROXITHROMYCIN TABLET FOR RESPIRATORY TRACT INFECTION." International Journal of Advance Research and Innovative Ideas In Education, vol. 11, no. 3, 2025, pp. 1735-1752.

IEEE Style

Mr. Abhijeet Kastode, Dnyaneshwar S Vyavhare, and Dr.Megha Salve, "FORMULATION & EVALUATION OF ROXITHROMYCIN TABLET FOR RESPIRATORY TRACT INFECTION," International Journal of Advance Research and Innovative Ideas In Education, vol. 11, no. 3, pp. 1735-1752, 2025.

Vancouver Style

Kastode Mr. Abhijeet, Vyavhare Dnyaneshwar S, Salve Dr.Megha. FORMULATION & EVALUATION OF ROXITHROMYCIN TABLET FOR RESPIRATORY TRACT INFECTION. International Journal of Advance Research and Innovative Ideas In Education. 2025;11(3):1735-1752.

Harvard Style

Kastode, Mr. Abhijeet, Vyavhare, Dnyaneshwar S, & Salve, Dr.Megha (2025) 'FORMULATION & EVALUATION OF ROXITHROMYCIN TABLET FOR RESPIRATORY TRACT INFECTION', International Journal of Advance Research and Innovative Ideas In Education, 11(3), pp. 1735-1752.

Chicago Style

Kastode, Mr. Abhijeet, Dnyaneshwar S Vyavhare, and Dr.Megha Salve. "FORMULATION & EVALUATION OF ROXITHROMYCIN TABLET FOR RESPIRATORY TRACT INFECTION." International Journal of Advance Research and Innovative Ideas In Education 11, no. 3 (2025): 1735-1752.

Turabian Style

Kastode, Mr. Abhijeet, Dnyaneshwar S Vyavhare, and Dr.Megha Salve. "FORMULATION & EVALUATION OF ROXITHROMYCIN TABLET FOR RESPIRATORY TRACT INFECTION." International Journal of Advance Research and Innovative Ideas In Education 11, no. 3 (2025): 1735-1752.