SOLUBILITY ENHANCEMENT OF CARVEDILOL USING MICROWAVE FUSION METHOD

Rahul K.Gharal; Manojkumar M. Nitalikar

SOLUBILITY ENHANCEMENT OF CARVEDILOL USING MICROWAVE FUSION METHOD

August 2021

Vol-7, Issue-4

Paper ID: 15258

ISSN: 2395-4396

Downloads: 0

Abstract & Details

Research Area

Pharmacy

Keywords

Carvedilol microwave fusion method solubility dissolution rate bioavailability amorphization

Abstract

The solubility is an important property of any drug. The absorption and bioavailability of drug is decided by its solubility in gastric fluids. The bioavailability of drug can be enhanced by enhancing its solubility. So, to achieve this goal, formulating solid dispersion is an effective approach to increase the dissolution rate and solubility of drug like carvedilol which have low water solubility. The water-soluble carriers or polymers used in formulation, assists in increasing the solubility and dissolution rate of drug with low hydrophilicity. Numbers of methods are present to formulate solid dispersions, but amongst them Microwave Fusion method is more efficient. Using this method Amorphization of drug can be accomplished which help to increase the dissolution rate and solubility of drug.

License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Author Information

#	Name	Institute / Affiliation
1	Rahul K.Gharal	Rajarambapu College of Pharmacy Kasegaon
2	Manojkumar M. Nitalikar	Rajarambapu College of Pharmacy Kasegaon

How to Cite

Use the following formats to cite this article in your research.

APA Style

K.Gharal, Rahul & Nitalikar, Manojkumar M. (2021). SOLUBILITY ENHANCEMENT OF CARVEDILOL USING MICROWAVE FUSION METHOD. International Journal of Advance Research and Innovative Ideas In Education, 7(4), 2430-2441.

MLA Style

K.Gharal, Rahul, and Manojkumar M. Nitalikar. "SOLUBILITY ENHANCEMENT OF CARVEDILOL USING MICROWAVE FUSION METHOD." International Journal of Advance Research and Innovative Ideas In Education, vol. 7, no. 4, 2021, pp. 2430-2441.

IEEE Style

Rahul K.Gharal and Manojkumar M. Nitalikar, "SOLUBILITY ENHANCEMENT OF CARVEDILOL USING MICROWAVE FUSION METHOD," International Journal of Advance Research and Innovative Ideas In Education, vol. 7, no. 4, pp. 2430-2441, 2021.

Vancouver Style

K.Gharal Rahul, Nitalikar Manojkumar M.. SOLUBILITY ENHANCEMENT OF CARVEDILOL USING MICROWAVE FUSION METHOD. International Journal of Advance Research and Innovative Ideas In Education. 2021;7(4):2430-2441.

Harvard Style

K.Gharal, Rahul & Nitalikar, Manojkumar M. (2021) 'SOLUBILITY ENHANCEMENT OF CARVEDILOL USING MICROWAVE FUSION METHOD', International Journal of Advance Research and Innovative Ideas In Education, 7(4), pp. 2430-2441.

Chicago Style

K.Gharal, Rahul and Manojkumar M. Nitalikar. "SOLUBILITY ENHANCEMENT OF CARVEDILOL USING MICROWAVE FUSION METHOD." International Journal of Advance Research and Innovative Ideas In Education 7, no. 4 (2021): 2430-2441.

Turabian Style

K.Gharal, Rahul and Manojkumar M. Nitalikar. "SOLUBILITY ENHANCEMENT OF CARVEDILOL USING MICROWAVE FUSION METHOD." International Journal of Advance Research and Innovative Ideas In Education 7, no. 4 (2021): 2430-2441.