Isolation and Antibiotics Susceptibility of Vibrio cholerae from various water sources in Makurdi, Nigeria

Science

ABSTRACT Cholera remains a global threat to public health especially in developing countries. Africa has been the continent with the highest number of officially reported cholera cases since 1996. It is impossible to prevent cholera from being introduced into an area but the spread of the disease within an area can be prevented through early detection, confirmation of cases, and appropriate preventive measures. Cholera remains a major public health problem in many developing countries. Cholera, an enteric diarrheal disease caused by the gram-negative bacterium, Vibrio cholerae (either type O1 or O139) continues to be a worldwide health concern. Robert Koch then successfully isolated the agent of cholera and created an awareness of cholera toxins in 1888. The research work is therefore important in several ways both to the health personnel and individuals within the society. This study will provide knowledge on Vibrio cholerae as a waterborne infectious agent and also suggest ways of preventing cholera outbreaks in our society. It will also be of importance to the health personnel and our local community health workers by providing awareness for various preventive measures to be put in place to avoid cholera outbreaks in our society. Antibiotics are biochemicals produced by microorganisms that inhibit the growth of or kill other microorganisms. Bacterial resistance is the capacity of bacteria to withstand the effects of antibiotics that are intended to kill or control them. The study will therefore also help us ascertain which antibiotic is most effective against Vibrio cholerae

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