COMPARATIVE PHYTOCHEMICAL ANALYSIS AND PHARMACOLOGICAL EVALUATION OF BERGENIA CILIATA AND RHODODENDRON CAMPANULATUM

Chemistry

Medicinal plants are important sources of bioactive compounds that provide therapeutic benefits in traditional and modern medicine. Bergenia ciliata and Rhododendron campanulatum are Himalayan medicinal plants widely used in traditional systems of medicine for treating various diseases such as kidney stones, inflammation, infections, and respiratory disorders. The present study focuses on a comparative phytochemical analysis and pharmacological evaluation of these two plants to identify their major bioactive constituents and biological activities. Plant samples were collected, dried, and subjected to extraction using methanol and aqueous solvents. Preliminary phytochemical screening revealed the presence of alkaloids, flavonoids, tannins, phenols, saponins, and glycosides in both plant extracts. Quantitative analysis indicated that Bergenia ciliata contained higher phenolic and flavonoid content, while Rhododendron campanulatum showed strong antioxidant and antimicrobial properties. Pharmacological evaluation was conducted using antioxidant assays, antimicrobial tests, and anti-inflammatory activity studies. Results demonstrated significant biological activity in both species, suggesting their potential as natural sources of therapeutic compounds. The comparative analysis highlights the medicinal significance of these plants and supports their use in pharmaceutical research and drug development.

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