Diagnostic accuracy of MRCP for cholangiocarcinoma in old age People

Medical

Background The most frequent primary hepatic malignancy is cholangiocarcinoma (CCA). Wide resections, the development of local treatment, and chemotherapy have all improved the prognosis in recent years. Objective To determine the diagnostic accuracy of MRCP for cholangiocarcinoma in old age People Methods A cross-sectional study was conducted at Park Hospital, New Delhi, India which was performed between February 2022 to March 2025. The total number of patients in our study were 100. The number of Male patients in our study were 57 and female were 43. For all patients, we did diagnostic tests, (CA-19-9), (MRCP, CT Scan) and lab tests. We also took the stages of cholangiocarcinoma. We took parameters of BMI (kg/m2) for all patients. We excluded pregnant women and children in our study. Data was tabulated and analyzed by SPSS version 27. Results In a current study total 100 patients were enrolled. The minimum age of patients were 42 years and the maximum age of the patients were 98 years. The mean age were 75.10±7.752 years. The minimum BMI of patients were 21 (kg/m2) and the maximum BMI 36 (kg/m2). The mean BMI (kg/m2) were 30.10±4.322. The minimum ALT were 72 and the maximum were 103 (u/l). The mean ALT (u/l) were 88.85±10.072. The minimum AST were 61 and the maximum were 86 (u/l). The mean AST (u/l) were 77.40±9.344. The minimum ALP were 142 and the maximum were 251 (u/l). The mean of ALP were 182.80±24.96 (u/l). The frequency of smoking were not present in 70 patients and were present in 30 patients. The frequency of CA-19-9 were negative in 25 patients and were positive in 75 patients. P-Value were 0.04. The frequency of diagnose of cholangiocarcinoma on CT scan were 28 and diagnose on MRCP were 72 and its percentage were 70%. The frequency of fever were not present in 84 patients and were present in 16 patients and its P-value were 0.05. The frequency of loss of appetite were not present in 71 patients and were present in 29 patients. The frequency of chronic liver disease were not present in 80 patients and were present in 20 patients. The frequency of diabetes were not present in 85 patients and were present in 15 patients. In our study P-Value were less than (< 0.05). Conclusion We concluded that Cholangiocarcinoma in older age people can diagnose accurately on MRCP as compared to other diagnostic modalities. Cholangiocarcinoma is common in old age people as compared to young population.

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