Review Coronary Heart Disease in Women

medicine

Abstract: Coronary heart disease is increasing in women all over the world. Due to the perception that women are less likely to have coronary heart disease there is still delay in diagnosis and treatment of women with coronary artery disease and acute coronary syndrome. Few coronary heart disease risk factors such as diabetes, dyslipidemia and obesity are more prominent in female as compared to male. There is gender wise differences in clinical presentation, pathophysiological mechanism and outcomes of acute coronary syndrome in women. Non- obstructive coronary artery disease is common in women. Microvascular dysfunction, coronary vasospasm, Spontaneous coronary artery dissection, plaque erosion is common pathophysiological mechanism of acute coronary syndrome in women. This article reviews the coronary artery disease risk factors. clinical presentation, pathophysiological mechanism and outcome of acute coronary syndrome and coronary artery disease in women. Conclusion: As recent evidences reveal that there is sex differences in coronary artery disease, women with coronary artery disease needs special guideline and strategy for diagnosis, management and prevention of coronary artery disease. Clinical trials focused on women’s health and adequate representation of women in clinical trials. is the need of today.

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