Lipid-Lowering Therapy and PCSK9 Inhibitors: The Function of PCSK9 inhibitors in Controlling High Cholesterol Level and Lowering the Possibility of Stroke

Medical

Ischemic strokes account for the majority of stroke cases. A stroke happens when the blood supply to the brain is abruptly interrupted. The insufficient blood flow can lead to brain damage and a range of physical and cognitive impairments. High cholesterol in the body is a significant risk factor for stroke. Reducing high cholesterol levels through lifestyle changes and medications can help lower the risk of stroke. PCSK9 inhibitors belong to a group of drugs employed for managing elevated cholesterol levels, particularly low-density lipoprotein cholesterol (LDL-C). These medications function by focusing on a specific protein within the body, known as PCSK9, which is responsible to control LDL receptor levels. Through the inhibition of PCSK9, these medications can efficiently reduce LDL cholesterol levels in the bloodstream. This review study was conducted to describe or evaluate the function of PCSK9 inhibitors in controlling high cholesterol level and lowering the possibility of stroke.

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