Study of Effect of Allium cepa extract on Haematological Parameter of Alloxan-treated Albino Mice ( Mus musculus)

Biological Science

Allium cepa is considered as herbal medicine. To investigate the effect of Allium cepa extract on diabetic mice was considered. Total 24 Albino mice (Mus musculus) were divided into three groups: a control group (8 individuals) and two experimental groups (8 individuals in each group). Mice of the control group were fed a normal diet with distilled water, no addition of Allium extracts to their diet. Mice of the experimental group were treated with Allaxon. The first experimental group of mice received freshly prepared aqueous extracts of Allium cepa for 28 days and the second experimental group didn’t receive Allium extract although they received a normal diet and distilled water like the control group. Red blood cell count, hemoglobin concentration, packed cell volume, and mean corpuscular volume, mean corpuscular hemoglobin concentration were determined after 28 days from administration of 1st dosage. Results showed that the Allium extract had a positive impact on the levels of the monitored hematological parameters. In the mice from the first experimental group, higher red blood cell count (4.77 million RBC/mm3), hemoglobin concentration (11.9gm%), and corpuscular volume(35.7%) were found. In the second and experimental group red blood cell count(3.31 million RBC/mm3), hemoglobin concentration(5.2gm%), and corpuscular volume(15.6%) were found lower than the control group.

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