REVIEW :TREATMENT ON RHEUMATOIDE ARTHIRITIS

Bpharmacy

Rheumatoid arthritis (RA) is a chronic, inflammatory, systemic autoimmune disorder characterized by symmetric inflammation of synovial joints leading to progressive erosion of cartilage and bone. The risk factors include age, gender, genetics, and environmental exposure (cigarette smoking, air pollutants, and occupational). As there is no cure for RA, the treatment goals are to reduce the pain and stop/ slow further damage. Here, we present a brief summary of various past and present treatment modalities to address the complications associated with RA. The clinical status of RA patients has improved in recent years due to medical advances in diagnosis and treatment, that have made it possible to reduce disease activity and prevent systemic complications. The most promising results were obtained by developing disease-modifying anti-rheumatic drugs (DMARDs), the class to which conventional synthetic, biologic, and targeted synthetic drugs belong. In the present work, we offer a comprehensive perspective on the management of RA, by centralizing the existing data provided by significant literature, emphasizing the importance of an early and accurate diagnosis associated with optimal personalized treatment in order to achieve better outcomes for RA patients. In addition, this study suggests future research perspectives in the treatment of RA that could lead to higher efficacy and safety profiles and lower financial costs.

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