Development of Effective Control Strategies for Stereotype and Genotype Monitoring

zoology

As far as arthropod-borne viral infections go, dengue fever is the most common in India. Because all four dengue virus serotypes have been found in Delhi, India's capital, the city is considered to be dengue virus endemic. Blood samples taken from suspected patients in New Delhi, India, during the post-monsoon season of 2015 were tested for the presence of dengue viruses and are described in this article. RT-PCR found dengue virus in 29% of the samples examined. The research found DENV-2, DENV-1, DENV-3, and DENV-4 in 66.66%, 22.22%, and 16.75% of the samples tested positive for each of the four DENV serotypes. The DENV2 serotype was found to predominate in the investigation. In addition, 22.22 percent of the samples tested positive for both DENV-1 and DENV-2 and 5.55 percent of samples tested positive for both DENV-2 and DENV-4 for co-infection. According to our findings, the age bracket of 21-30 years old had the highest percentage of dengue-positive patients. DNA sequencing of individual serotypes will also provide information on the circulating genotypes in this area. Studying illness severity in connection to various serotypes and concurrent infections will also add to our understanding of how this virus spreads. Serotype and genotype monitoring will aid in the development of effective control strategies for DENV.

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.