ASSESS THE SIGNIFICANCE OF METABOLIC ACIDOSIS IN THE PATIENTS WITH ACUTE STEMI AT A SELECTED HOSPITAL

critical care

Coronary Artery Disease (CAD) is the leading cause of death globally where India has the highest burden. It causes 3 million deaths per year, accounting for 25% of all mortality in India. Hospitals statistics reveal that 20-25 % of all medical admissions are due to Coronary artery disease (WHO, 2017). Acute myocardial infarction (AMI) is a cardiac emergency. The clinical diagnosis of AMI requires an integrated assessment of the history especially with reference to chest pain along with some combination of indirect evidences of myocardial infarction using biochemical, electrocardiographic, and imaging modalities. In the United States, nearly one million patients suffer from AMI per year (AHA, 2004). Objectives: i. To assess the arterial blood gases among the patients with acute STEMI. ii. To assess the physiological parameters and biochemical markers with acute STEMI. iii. To assess the prognosis of the patients with acute STEMI. iv. To associate acid base status (Metabolic acidosis) with acute STEMI. v. To associate the physiological parameters and biochemical markers with acute STEMI. vi. To correlate metabolic acidosis and acute STEMI. Methodology: Research approach: quantitative approach, a descriptive research design for 43 samples by Non- probability convenient sampling technique. Results: It shows that increased mortality rate was associated with low pH and bicarbonate levels of the patients with acute STEMI had shown statistically significant association with STEMI at p <0.05

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