EFFECTS OF YEMENI PUMPKIN FRUIT ON THE HUMAN PLASMA GLUCOSE LEVEL, HbA1c & LIPID PROFILE

clinical pharmacology

Pumpkin (CucurbitapepoL) is a widely desirable fruit. There are no more published articles dealing with pumpkin fruits as much as seeds, and its functionality as a medicinal foodstuff. In this study, the effect of pumpkin fruit on diabetes and dyslipidemia was investigated. The study involved 20 participants that received a simple explanation for the aim of the study as an ethical issue. The participants were divided into two groups first group were 10 healthy adults as control, second group were 10 diabetic mellitus and cardiovascular patients such as hypertension, ischemic heart disease and dyslipidemia.Certain biological parameters including Fasting Plasma Glucose (FPG), Glycosylated Hemoglobin (HbA1c), Total Cholesterol (T-Chol), Tri-Glyceride (TG), Low Density Lipoproteins (LDL), and High Density Lipoproteins (HDL) were laboratory investigated. The results showed that the eaten Pumpkin fruits significantly (P < 0.05) reduced fasting plasma glucose amongthe patients group,while increases HDL level in both groups. But, the levels of other investigated parameters were not significantly (P > 0.05) affected. In conclusion, the study revealed that, the pumpkin fruit could be a suitable medicine for diabetic mellitus and low HDL patients with significantly levels P value (0.0417, 0.0029) respectively.

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.