Current situation and development of local antimicrobial agents in revision arthroplasty for periprosthetic joint infection (PJI)

Medical

Abstract Aim To determine current situation and development of local antimicrobial agents in revision arthroplasty for periprosthetic joint infection (PJI). Methods A cross-sectional study was conducted at First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang China, which was performed between March 2022 and January 2024, The total number of patients in our study were 110. The number of Male patients were 43 and females were 67. Hip patients were more as compared to knee joint. In 110 consecutive patients who underwent for blood tests and Procedures. We took a brief history from all patients. Data was tabulated and analyzed by SPSS version 25. Results The mean value of all enrolled 110 patients was 62.36±13.0 years. The mean ESR, CRP and recovery time were 37.15±5.45, 6.85±2.65 and 4.69±1.0 respectively. Out of total 43(39.1%) were male and 67(60.9%) were female. 82(74.5%) patients were suffering from joint pain. Site of Arthoplasty were Right knee 25(22.7%), Right hip 39(35.5%), Left knee 18(16.4%) and Right hip 28(25.5%). 103 (93.6%) patients were suffering from Erythema. Patients with joint swelling were Joint swelling 92(83.6%). 102(92.7%) patients were suffering from fever. Gram-positive bacteria and gram-negative bacteria were found in 72 (65.5%) and 38(34.5) patients respectively. Complications were found in terms of Hematoma (60.9%) and Superficial SSI (36.3%). Stratification of bacteria on the basis of different variables were given in table 3 with insignificant P-Value in all cases. P-value for gender is 0.3 and P- value of complication 0.36 Conclusion Local antimicrobial agents in revision arthroplasty for periprosthetic joint infection (PJI) is one of the best methods to recover patients quickly with a low complication rate. The recovery time of patients from Periprosthetic joint infection (PJI) was 3 to 6 weeks. Gram-positive bacteria were more in our study as compared to gram-negative bacteria. We can diagnose patients of Periprosthetic joint infection (PJI) on blood test C-reactive protein (CRP) and Erythrocyte sedimentation rate (ESR). In our study females were more as compared to males.

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.