MENISCAL ALLOGRAFT TRANSPPLANTATION : AN OVERVIEW AND FUTURE DIRECTIONS

Biological and Medical Sciences

The structure of the menisci allows the effective distribution of load across the knee joint. Even though our first priority goes to meniscus-preserving surgery, but many tears are irreparable, and many repairs are not successful. It is widely accepted that partial meniscectomy leads to early onset of osteoarthritis (OA). Meniscal allograft transplantation (MAT) was developed as a means of treating the symptoms of compartmental overload after meniscectomy and numerous case series have reported a significant improvement in knee function with reasonable rates of complication and survival, but randomized controlled trials have not been undertaken. Meniscal allograft transplantation has been performed for more than 30 years and numerous case series have consistently reported as protective of cartilage. The main goal of this review article is to provide an overview and current status of the role of MAT and also discussed the directions to advance the MAT in the future.

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