IRON AND VITAMIN-B12 LEVEL IN ORAL SUBMUCOSAL FIBROSIS(OSMF) PATIENTS

DENTISTRY

Background: OSMF is a well recognised potentially malignant condition in oral cavity it may lead to oral cancer ,a potentially fatal disease leading to raise in incidence among younger and older people. Trace elements plays a important role in growth and maintaining the integrity of cells and tissues. Impaired level of such elements may impair cellular and physiological function. In this study I examined copper and zinc ratio in OSMF patients. Aim and objective: To evaluate the level of serum iron and VIT. B12 ratio in serum of patients containing OSMF and to evaluate whether copper and zinc could be used as prognostic indicators in the development of OSMF. Materials and methods: 60 age and sex matched individuals of OSMF and healthy controls are taken for this study. Under aseptic precautions 5 ml of venous blood was collected and serum treatment iron and B12 is estimated by spectrophotometric method.

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