OXIDATION OF THE DRUG TRIMETAZIDINE BY N-BROMOSUCCINIMIDE IN AQUEOUS MEDIUM – A KINETIC STUDY

August 2020
Vol-6, Issue-4
Paper ID: 12464
ISSN: 2395-4396
Downloads: 0

Abstract & Details

Research Area
CHEMICAL SCIENCE
Keywords
Trimetazidine N-bromo succinamide stoichiometry oxidation rate law
Abstract
The kinetics of oxidation of Trimetazidine by N-bromo succinamide in perchloric acid medium has been studied at 303K. The products of oxidation were tested and stoichiometry of reaction was determined. The rate of reaction was observed to show a first order dependence on oxidant, fractional order on substrate and inverse fractional order on [H+]. The dielectric constant has a slight negative effect. The unchanged rate with ionic strength indicate involvement of non ionic species in rate determining step. The kinetic runs were performed at different temperature and thermodynamic parameters were computed. A mechanism consistent with observed parameters is proposed. Rate law is derived.
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Author Information

# Name Institute / Affiliation
1 H.P. JAYADEVAPPA, Department of Chemistry, Yuvaraja College, University of Mysore, Mysuru, India

How to Cite

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APA Style
JAYADEVAPPA,, H.P. (2020). OXIDATION OF THE DRUG TRIMETAZIDINE BY N-BROMOSUCCINIMIDE IN AQUEOUS MEDIUM – A KINETIC STUDY. International Journal of Advance Research and Innovative Ideas In Education, 6(4), 1412-1418.
MLA Style
JAYADEVAPPA,, H.P.. "OXIDATION OF THE DRUG TRIMETAZIDINE BY N-BROMOSUCCINIMIDE IN AQUEOUS MEDIUM – A KINETIC STUDY." International Journal of Advance Research and Innovative Ideas In Education, vol. 6, no. 4, 2020, pp. 1412-1418.
IEEE Style
H.P. JAYADEVAPPA,, "OXIDATION OF THE DRUG TRIMETAZIDINE BY N-BROMOSUCCINIMIDE IN AQUEOUS MEDIUM – A KINETIC STUDY," International Journal of Advance Research and Innovative Ideas In Education, vol. 6, no. 4, pp. 1412-1418, 2020.
Vancouver Style
JAYADEVAPPA, H.P.. OXIDATION OF THE DRUG TRIMETAZIDINE BY N-BROMOSUCCINIMIDE IN AQUEOUS MEDIUM – A KINETIC STUDY. International Journal of Advance Research and Innovative Ideas In Education. 2020;6(4):1412-1418.
Harvard Style
JAYADEVAPPA,, H.P. (2020) 'OXIDATION OF THE DRUG TRIMETAZIDINE BY N-BROMOSUCCINIMIDE IN AQUEOUS MEDIUM – A KINETIC STUDY', International Journal of Advance Research and Innovative Ideas In Education, 6(4), pp. 1412-1418.
Chicago Style
JAYADEVAPPA,, H.P.. "OXIDATION OF THE DRUG TRIMETAZIDINE BY N-BROMOSUCCINIMIDE IN AQUEOUS MEDIUM – A KINETIC STUDY." International Journal of Advance Research and Innovative Ideas In Education 6, no. 4 (2020): 1412-1418.
Turabian Style
JAYADEVAPPA,, H.P.. "OXIDATION OF THE DRUG TRIMETAZIDINE BY N-BROMOSUCCINIMIDE IN AQUEOUS MEDIUM – A KINETIC STUDY." International Journal of Advance Research and Innovative Ideas In Education 6, no. 4 (2020): 1412-1418.

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