Epidemiology of ebola virus : transmission, symptoms, treatment, prevention and control

Zoology

Ebola virus also known as Ebola hemorrhagic fever or Ebola ,is caused by Ebola virus (EBOV).Ebola virus is a linear non segmented, single negative stranded RNA virus .Up to 90% of those who contract the Ebola virus (EBOV) die from the severe hemorrhagic fever it causes. Interest in this virus has increased as outbreaks have become more frequent and since EBOV was added to the category A list of potential biothreat agents. The understanding of the pathogenic mechanisms behind Ebola haemorrhagic fever (EHF) has significantly increased as a result of many investigations conducted in animal models. Vascular dysfunction and immune response impairment are two important elements in the pathogenesis of EBOV. Here, we make an effort to condense the state of our understanding of EBOV pathogenesis, focusing on these two aspects as well as recent developments in the creation of vaccines and potential therapies.

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