CT scan in the early assessment of patients with acute pancreatitis

Medical

Abstract Background Guidelines recommend that contrast-enhanced computed tomography (CT) should be carried out 72 hours after onset of an attack of acute pancreatitis (AP). However, the exact time beyond 72 hours at which CT will produce the best diagnostic yield for local complications Objective To determine CT scan in the early assessment of patients with acute pancreatitis Methods A cross-sectional study was conducted at Jinnah Hospital Lahore Pakistan, which was performed between September 2020 to December 2023, The name of CT scan machine which was used in our study was Toshiba 64 slice and its slice thickness was 0.5 mm. Iodine-based contrast is used. The total number of patients in our study were 100. The number of Male patients were 45 and female were 55. For all patients, we did diagnostic tests CECT. BMI parameter of every patient we took. We also took detailed history from the patients about the signs and symptoms. Data was tabulated and analyzed by SPSS version 26. Result In a current study total 100 patients were enrolled. The minimum age of patients were 42 years and the maximum age of the patients were 81 years. The mean age were 57.95±11.112 years. The minimum BMI of patients were 25 (Kg/m2) and the maximum BMI were 31 (Kg/m2). The mean BMI were 27.55±1.83 (Kg/m2). The minimum serum amylase were 300 (U/L) and the maximum serum amylase were 700 (U/L). The mean serum amylase were 376.55±87.42 (U/L). The minimum serum Lipase were 350 (U/L) and the maximum serum Lipase were 820 (U/L). The mean serum Lipase were 438.0±103.08 (U/L). the frequency of Female patients were 55 and the percentage were 55. The cumulative percent were same 55.0. The frequency of male patients were 45 and the percentage were 45. Total number of patients were 100 (100 %) in our study. he frequency of gallstones were absent in 54 patients and its percentage were 54% and the frequency of gallstone were present in 46 patients and its percentage were 46%. P-value is <0.04 in our study. Conclusion We concluded that the most common etiology of acute pancreatitis is Gallstone. Early CT was a good indicator of the severity of acute pancreatitis in our selected population. Pancreatic necrosis is estimated on early, contrast-enhanced CT and seen only in patients having severe disease. CECT is a good modality for the early detection of AP. Females were more in our study as compared to males.

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