CURCUMIN- AND FISH OIL-LOADED SPONGOSOME AND CUBOSOME NANOPARTICLES: A PARADIGM SHIFT IN HERBAL DRUG DELIVERY SYSTEM

Pharmaceutical Sciences

: The aim of the present cram was to look at the potential for neuroprotective effects of sponges enriched with curcumin and fish oil. Curcumin is a holy grail molecule that can be utilized in a variety of diseases. As curcumin (CU) and other phytochemical antioxidant compounds are water-insoluble, delivery vehicles are necessary to improve their bioavailability for in vivo uses. When used in combination therapy, lipid nanoparticles (NPs) with internal self-assembled liquid crystalline structures show great promise as secure drug delivery vehicles. Apoptosis caused by oxidative stress is a prevalent factor in the death of neurons as neurodegenerative disorders advance. The improvement of drug delivery over traditional drug delivery, or the conventional strategy to provide target specificity and increase the bioavailability of phytochemicals, is the main emphasis of the current review. The development of tailored medicines for the treatment of neurological illnesses holds promise when using nanoscale delivery technologies. This development in herbal medicine delivery appears to be a feasible and promising carrier capable of giving a more effective therapeutic result

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