A Review on: The Potential Role of Silver Nanoparticles in Cancer Diagnosis and Treatment

Department of Pharmacology (M.pharm)

This review's main goal is to provide the results of studies on the anticancer properties of silver nanoparticles. Nano biotechnology, a new branch of Nano science, employs nano-based technologies for a variety of biological applications. The prospect of utilizing therapeutic nanoparticles in the detection and treatment of human cancer has emerged as a result of this fast emerging field of Nano science. Silver nanoparticles (AgNPs) are most widely used in various clinical applications because of their antibacterial properties. Apart from antibacterial capabilities, AgNPs have unique cytotoxic effects against mammalian cells, which may make silver-based nanoparticles useful for tumor treatment. Here in this review, due attention has been given to highlight the anticancer properties of silver nanoparticles along with their mechanistic pathway. AgNPs are effective anticancer agents that influence the cell cycle, prevent the growth of cancer cells, cause oxidative stress, and spread programmed cell death (apoptosis). Understanding the mechanistic action of AgNPs responsible for their therapeutic efficacy will help to design anti-cancer therapies and treatments as a potential therapeutic tool.

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