method development and validation of Gemfibrozil by RP-HPLC in bulk and Pharmaceutical dosage forms
Abstract & Details
Research Area
Pharmacy
Keywords
Gemfibrozil
RP-HPLC
Validation
Method Development
Abstract
A simple, specific and accurate reverse phase high performance liquid chromatographic method
was developed for the determination Gemfibrozil in bulk and pharmaceutical dosage form. The
column used was Agilent Zorbax C8 (150 ×4.6mm, 5µ) in gradient mode, with mobile phase
containing SolventMethanol, 0.05%OPA, Water ratio 40+60 the flow rate was 0.7 mL/ min and
eluents was monitored at 276 nm. The retention time Gemfibrozil was 5.158 min, respectively.
The linearity for Gemfibrozil was in the range of 30-450 µg/ml respectively. The recovery of
Gemfibrozil was found to be 99.5%, respectively. The proposed method was validated and
successfully applied to the estimation of Gemfibrozil in capsule dosage form.
License
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Author Information
| # | Name | Institute / Affiliation |
|---|---|---|
| 1 | Maqsud Patel | Ali Alana college of pharmacy akkalkuwa |
| 2 | Siddik Patel | Ali Alana college of pharmacy akkalkuwa |
| 3 | G.J.Khan | Ali Alana college of pharmacy akkalkuwa |
How to Cite
Use the following formats to cite this article in your research.
APA Style
Patel, Maqsud, Patel, Siddik, & G.J.Khan (2022). method development and validation of Gemfibrozil by RP-HPLC in bulk and Pharmaceutical dosage forms. International Journal of Advance Research and Innovative Ideas In Education, 8(4), 1050-1072.
MLA Style
Patel, Maqsud, et al. "method development and validation of Gemfibrozil by RP-HPLC in bulk and Pharmaceutical dosage forms." International Journal of Advance Research and Innovative Ideas In Education, vol. 8, no. 4, 2022, pp. 1050-1072.
IEEE Style
Maqsud Patel, Siddik Patel, and G.J.Khan, "method development and validation of Gemfibrozil by RP-HPLC in bulk and Pharmaceutical dosage forms," International Journal of Advance Research and Innovative Ideas In Education, vol. 8, no. 4, pp. 1050-1072, 2022.
Vancouver Style
Patel Maqsud, Patel Siddik, G.J.Khan. method development and validation of Gemfibrozil by RP-HPLC in bulk and Pharmaceutical dosage forms. International Journal of Advance Research and Innovative Ideas In Education. 2022;8(4):1050-1072.
Harvard Style
Patel, Maqsud, Patel, Siddik, & G.J.Khan (2022) 'method development and validation of Gemfibrozil by RP-HPLC in bulk and Pharmaceutical dosage forms', International Journal of Advance Research and Innovative Ideas In Education, 8(4), pp. 1050-1072.
Chicago Style
Patel, Maqsud, Siddik Patel, and G.J.Khan. "method development and validation of Gemfibrozil by RP-HPLC in bulk and Pharmaceutical dosage forms." International Journal of Advance Research and Innovative Ideas In Education 8, no. 4 (2022): 1050-1072.
Turabian Style
Patel, Maqsud, Siddik Patel, and G.J.Khan. "method development and validation of Gemfibrozil by RP-HPLC in bulk and Pharmaceutical dosage forms." International Journal of Advance Research and Innovative Ideas In Education 8, no. 4 (2022): 1050-1072.
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