STUDY OF CHLORHEXIDINE ALCOHOL AND POVIDONE IODINE FOR SURGICAL SITE ANTISEPSIS IN UNCOMPLICATED EMERGENCY OPEN APPENDECTOMY
Abstract & Details
Research Area
Biological and Medical Sciences
Keywords
Surgical site infections (SSIs)
Skin antisepsis
Chlorhexidine alcohol (CHA)
Povidone iodine (PI)
Uncomplicated Emergency Open Appendectomy.
Abstract
Introduction: Surgical site infections (SSIs) cause severe morbidity and mortality along with enormous health costs. Skin antisepsis with chlorhexidine alcohol solutions has demonstrated superiority to povidone-iodine for the prevention of SSIs. Our objective was to determine if chlorhexidine-alcohol reduces the rate of SSIs in uncomplicated emergency open appendectomy compared with povidone-iodine and also analyze risk factors associated with SSIs.
Materials and Methods: This study was carried out at Tribhuvan University Teaching Hospital, Kathmandu. A total of 88 patients with acute uncomplicated appendicitis who underwent uncomplicated emergency open appendectomy were included. The protocols for antisepsis were use of 10% povidone-iodine (n = 44) and 2% chlorhexidine in 80% isopropyl alcohol (n= 44) over the surgical site. The rates of SSIs as defined by the Centers for Disease Control and Prevention (CDC) and risk factors for the occurrence of SSIs were determined.
Result: The two groups of patients were similar in regard to baseline characteristics and medical history. Thirteen patients (14.77%) developed superficial SSI. There was no significant difference between the two study groups in incidence of SSI (relative risk,0.57; 95% CI, 0.17 to 1.92). Antisepsis with chlorhexidine-alcohol was not associated with a reduction in the overall rate of SSI (11.4 % vs 18.2%, p= 0.37). Smoking was found to be associated with SSI in povidone-iodine group (p=0.042).
Conclusion: This study demonstrates that chlorhexidine-alcohol showed similar antiseptic role as povidone-iodine in patients undergoing uncomplicated emergency open appendectomy in preventing SSI. This is of vital clinical importance for developing country like Nepal where povidone-iodine is the antisepsis of choice in daily surgical practice.
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Author Information
| # | Name | Institute / Affiliation |
|---|---|---|
| 1 | Susan Pradhan | Pokhara Academy of Health Sciences, Pokhara, Nepal |
| 2 | Sadikshya Shrestha | Tribhuvan University Teaching Hospital, Kathmandu, Nepal |
| 3 | Sandip Shrestha | Pokhara Academy of Health Sciences, Pokhara, Nepal |
| 4 | Ajay K.C | Pokhara Academy of Health Sciences, Pokhara, Nepal |
| 5 | Sandesh Doranga | Pokhara Academy of Health Sciences, Pokhara, Nepal |
| 6 | Sangam Rayamajhi | Tribhuvan University Teaching Hospital, Kathmandu, Nepal |
| 7 | Jayan Man Shrestha | Tribhuvan University Teaching Hospital, Kathmandu, Nepal |
How to Cite
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APA Style
Pradhan, Susan, Shrestha, Sadikshya, Shrestha, Sandip, K.C, Ajay, Doranga, Sandesh, Rayamajhi, Sangam, & Shrestha, Jayan Man (2022). STUDY OF CHLORHEXIDINE ALCOHOL AND POVIDONE IODINE FOR SURGICAL SITE ANTISEPSIS IN UNCOMPLICATED EMERGENCY OPEN APPENDECTOMY. International Journal of Advance Research and Innovative Ideas In Education, 8(3), 5406-5415.
MLA Style
Pradhan, Susan, et al. "STUDY OF CHLORHEXIDINE ALCOHOL AND POVIDONE IODINE FOR SURGICAL SITE ANTISEPSIS IN UNCOMPLICATED EMERGENCY OPEN APPENDECTOMY." International Journal of Advance Research and Innovative Ideas In Education, vol. 8, no. 3, 2022, pp. 5406-5415.
IEEE Style
Susan Pradhan, Sadikshya Shrestha, Sandip Shrestha, Ajay K.C, Sandesh Doranga, Sangam Rayamajhi, and Jayan Man Shrestha, "STUDY OF CHLORHEXIDINE ALCOHOL AND POVIDONE IODINE FOR SURGICAL SITE ANTISEPSIS IN UNCOMPLICATED EMERGENCY OPEN APPENDECTOMY," International Journal of Advance Research and Innovative Ideas In Education, vol. 8, no. 3, pp. 5406-5415, 2022.
Vancouver Style
Pradhan Susan, Shrestha Sadikshya, Shrestha Sandip, K.C Ajay, Doranga Sandesh, Rayamajhi Sangam, et al. STUDY OF CHLORHEXIDINE ALCOHOL AND POVIDONE IODINE FOR SURGICAL SITE ANTISEPSIS IN UNCOMPLICATED EMERGENCY OPEN APPENDECTOMY. International Journal of Advance Research and Innovative Ideas In Education. 2022;8(3):5406-5415.
Harvard Style
Pradhan, Susan, Shrestha, Sadikshya, Shrestha, Sandip, K.C, Ajay, Doranga, Sandesh, Rayamajhi, Sangam, & Shrestha, Jayan Man (2022) 'STUDY OF CHLORHEXIDINE ALCOHOL AND POVIDONE IODINE FOR SURGICAL SITE ANTISEPSIS IN UNCOMPLICATED EMERGENCY OPEN APPENDECTOMY', International Journal of Advance Research and Innovative Ideas In Education, 8(3), pp. 5406-5415.
Chicago Style
Pradhan, Susan, et al. "STUDY OF CHLORHEXIDINE ALCOHOL AND POVIDONE IODINE FOR SURGICAL SITE ANTISEPSIS IN UNCOMPLICATED EMERGENCY OPEN APPENDECTOMY." International Journal of Advance Research and Innovative Ideas In Education 8, no. 3 (2022): 5406-5415.
Turabian Style
Pradhan, Susan, et al. "STUDY OF CHLORHEXIDINE ALCOHOL AND POVIDONE IODINE FOR SURGICAL SITE ANTISEPSIS IN UNCOMPLICATED EMERGENCY OPEN APPENDECTOMY." International Journal of Advance Research and Innovative Ideas In Education 8, no. 3 (2022): 5406-5415.