Recent Developments on Bio Products and Bioprocess Intensification in Biopharmaceutical Manufacturing

Chemical Engineering and Bio Technology

Bioprocessing for cell treatment is an order that scaffolds the cell treatment and bioprocessing (i.e. biopharmaceutical manufacturing) fields and is a sub-field of bioprocess construction. The aim of the present work is to develop optimum operating conditions for a sustainable, reproducible and robust manufacturing processes for the development of microbial feedstock. Bio-oil is produced by a pyrolysis process that involves the rapid thermal decomposition of organic materials such as wood and agricultural biomass, in the absence of oxygen. The quality of the bio-oil is dependent upon the type of biomass used. Process Intensification applies to replacing complex technologies with smaller, less expensive and more efficient integrated equipment and processes. It integrates, ideally, as many unit activities as possible into multifunctional ones for use in the chemical and biological industries. In comparison with traditional bio-processing technologies, emerging PI technologies such as membrane reactor, high-frequency magnetic impulse cavitation reactor and ultrasonic cavitation reactor tend to be cost-effective and environmentally friendly. Using different PI techniques, several bio-products were developed commercially, which lowered the cost of production and resulted in an increased yield of almost 87.5% as compared to the conventional bioprocess techniques. The present process for obtaining a blending or ageing additive from oak wood comprises of mixing red oak wood in subdivided or particulate form with water or aqueous alcoholic liquid containing up to, for example, 50% by weight of alcohol (e.g. wine or spirit).

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